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Index > Protein center > ADAM2(Gene name) > Human
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  • ADAM2 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 2 (Protein name ),  ADAM2_HUMAN from NCBI database.
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  • Gene name:
    ADAM2(FTNB);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 2(ADAM 2);
    Alternative:
    Fertilin subunit beta;Cancer/testis antigen 15(CT15);PH30-beta;PH-30(PH30);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    735
    Sequence:
    50:
    MWRVLFLLSG | LGGLRMDSNF | DSLPVQITVP | EKIRSIIKEG | IESQASYKIV | 
    100:
    IEGKPYTVNL | MQKNFLPHNF | RVYSYSGTGI | MKPLDQDFQN | FCHYQGYIEG | 
    150:
    YPKSVVMVST | CTGLRGVLQF | ENVSYGIEPL | ESSVGFEHVI | YQVKHKKADV | 
    200:
    SLYNEKDIES | RDLSFKLQSV | EPQQDFAKYI | EMHVIVEKQL | YNHMGSDTTV | 
    250:
    VAQKVFQLIG | LTNAIFVSFN | ITIILSSLEL | WIDENKIATT | GEANELLHTF | 
    300:
    LRWKTSYLVL | RPHDVAFLLV | YREKSNYVGA | TFQGKMCDAN | YAGGVVLHPR | 
    350:
    TISLESLAVI | LAQLLSLSMG | ITYDDINKCQ | CSGAVCIMNP | EAIHFSGVKI | 
    400:
    FSNCSFEDFA | HFISKQKSQC | LHNQPRLDPF | FKQQAVCGNA | KLEAGEECDC | 
    450:
    GTEQDCALIG | ETCCDIATCR | FKAGSNCAEG | PCCENCLFMS | KERMCRPSFE | 
    500:
    ECDLPEYCNG | SSASCPENHY | VQTGHPCGLN | QWICIDGVCM | SGDKQCTDTF | 
    550:
    GKEVEFGPSE | CYSHLNSKTD | VSGNCGISDS | GYTQCEADNL | QCGKLICKYV | 
    600:
    GKFLLQIPRA | TIIYANISGH | LCIAVEFASD | HADSQKMWIK | DGTSCGSNKV | 
    650:
    CRNQRCVSSS | YLGYDCTTDK | CNDRGVCNNK | KHCHCSASYL | PPDCSVQSDL | 
    700:
    WPGGSIDSGN | FPPVAIPARL | PERRYIENIY | HSKPMRWPFF | LFIPFFIIFC | 
    735:
    VLIAIMVKVN | FQRKKWRTED | YSSDEQPESE | SEPKG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    String:
    UniGene:
    SMR:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADAM 2
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    ELISA Kit for Human ADAM 2
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    CLIA Kit for Human ADAM 2
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    96T
    CLIA Kit for Human ADAM 2
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    U14287h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human ADAM 2
    Cat.:
    U14287m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ADAM 2
    MSDS:
    Please sign in first.
    CLIA Kit for Human ADAM 2
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    U14287r
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    Polyclonal Antibody for Human ADAM 2
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    P14287Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ADAM 2
    Cat.:
    P14287Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ADAM 2
    Polyclonal Antibody for Human ADAM 2
    Polyclonal Antibody for Human ADAM 2
    Cat.:
    P14287Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ADAM 2
    Monoclonal Antibody for Human ADAM 2
    Monoclonal Antibody for Human ADAM 2
    Monoclonal Antibody for Human ADAM 2
    Monoclonal Antibody for Human ADAM 2
    Protein for Human ADAM 2
    Protein for Human ADAM 2
    Protein for Human ADAM 2
    Protein for Human ADAM 2
    Protein for Human ADAM 2

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    Linearity
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    References
    1. 1.
      "Human fertilin beta: identification, characterization, and chromosomal mapping of an ADAM gene family member."
      Vidaeus C.M. , von Kap-Herr C. , Golden W.L. , Eddy R.L. , Shows T.B. , Herr J.C.
      Mol. Reprod. Dev.46:363-369(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    3. 3.
      "Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB)."
      Burkin H.R. , Burkin D.J. , Davey P.M. , Griffin D.K. , Affara N.A.
      Genomics40:190-192(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    4. 4.
      "Nucleotide sequence of the human fertilin beta transcript."
      Hall L. , Frayne J.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
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